Nephrotic Syndrome is the name given to a condition where you find kidneys leaking protein into the urine. This causes large amounts of protein to leak out into the urine resulting in fluid retention in your body. Normally, urine should contain almost no protein but when its presence is detected in the urine, the protein levels available in blood diminish as a result. The fluid retention causes swelling of ankles and legs and extra fluid may also accumulate in the abdomen and around the face. This is especially noticeable after waking up in the morning. The abdomen and face are more affected in case of children and young adults.

The protein leakage from kidney may make the urine frothy. It also causes lethargy. There can also be some other serious effects like increased risk of infection, raised blood cholesterol, and increased risk of blood clotting. A renal biopsy is the most significant test in detecting nephrotic syndrome. Using local anesthesia, a needle is placed into the kidney through the back. The patient needs to be admitted in the hospital for this procedure.

Nephrotic syndrome is divided into different types based on the appearances of the kidney under the microscope while performing renal biopsy. Some are caused due to rare allergic reactions to medicines, infections like Hepatitis B, and diabetes. But in most cases, the cause remains unknown. Different kinds of nephrotic syndrome respond differently to the treatments administered.

In children the syndrome is usually caused by a condition that responds easily to treatment, so treatment is undertaken first, and the biopsy is performed only if the protein leak is not pain in lower left abdomen cured.

Long term complications may occur in people with severe disease which is unresponsive to treatment. Extended years of protein leakage from kidneys may result in kidney failure, and some people will require dialysis or a transplant to keep them well. The renal biopsy and other tests help in predicting such serious consequences.

A variety of treatments are available for kidneys leaking protein. The complications of fluid retention can be dealt with by taking diuretic tablets. These force the kidneys to discharge more salt and water in the urine. You may cut down on salt and increase your fluid intake for better results. It is important that diuretic treatment is carefully controlled by taking blood tests and weighing on a regular basis. Often people suffering from kidney problems also suffer from high blood pressure and this should be controlled.

The treatment for the disease itself depends on the type of kidney disease shown by the biopsy and treatment is given to control the cause of nephrotic syndrome. As such, the different types of kidney diseases indicate different things for your health in the future. Some of the rare causes that lead to a nephrotic syndrome include allergic reactions to medicines, infections such as Hepatitis B and diabetes is also known to lead to this condition. But in some rare cases the actual cause may not be diagnosed at all. Generally, different types respond to the treatments in a different way.

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